Tuesday, January 31, 2012

Cancer Drugs Affect Mouse Genomes for Generations

Cancer Drugs Affect Mouse Genomes for Generations:

By Heidi Ledford of Nature magazine

Three common chemotherapy drugs cause DNA mutations not only in mice that receive treatment, but also in their offspring, according to a study published today in the Proceedings of the National Academy of Sciences USA .

The results suggest that the genome in treated mice became destabilized yielding new mutations long after exposure to the drugs has ceased. [More]